Please consult the Biosafety in Microbiological and Biomedical Laboratories, 4th edition for information about conducting ABSL-4 studies. The equipment and physical plant needed to safely conduct ABSL-4 studies can cost millions of dollars, and training needs are extraordinary. Very few facilities can support ABSL-4 work- they include the Centers for Disease Control and Prevention and the Plum Island facility.
http://www.cdc.gov/biosafety/publications/bmbl5/BMBL5_sect_V.pdf