“(d) IACUC review of activities involving animals.
(1) In order to approve proposed activities or proposed significant changes in ongoing activities, the IACUC shall conduct a review of those components of the activities related to the care and use of animals and determine that the proposed activities are in accordance with this subchapter;”
From PHS Policy, Section IV.B.-
“B. Functions of the Institutional Animal Care and Use Committee As an agent of the institution, the IACUC shall with respect to PHS – conducted or supported activities:
Review and approve, require modifications in (to secure approval) or withhold approval of those components of PHS-conducted or supported activities related to the care and use of animals as specified in IV.C. of this Policy;
Review and approve, require modifications in (to secure approval), or withhold approval of proposed significant changes regarding the use of animals in ongoing activities; and
Be authorized to suspend an activity involving animals in accordance with the specifications set forth in IV.C.6 of this Policy.”